LibGuides: Medicinal & Biological Chemistry: Websites & Books

General Biochemistry Resources

Glossary of Biochemistry and Molecular Biology
Searchable dictionary of 3000 terms from biochemistry and genetics.
Talking Glossary of Genetic Terms
Terms in genetics and biochemistry are defined, with audio pronunciations, illustrations, and animations. From the National Human Genome Project at NIH.
The PubChem Project
PubChem provides information on the biological activities of small molecules.
BLAST - Basic Local Alignment Search Tool
BLAST finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.
BRENDA Enzyme Database
A comprehensive database of enzymes with original literature references, organism-related information, etc.
ChEMBLdb
Database of bioactive drug-like small molecules, it contains 2-D structures, calculated properties (e.g. logP, Molecular Weight, Lipinski Parameters, etc.) and abstracted bioactivities (e.g. binding constants, pharmacology and ADMET data)
Kyoto Encyclopedia of Genes and Genomes
KEGG is a database resource for understanding high-level functions and utilities of the biological system, such as the cell, the organism and the ecosystem, from genomic and molecular-level information.
Chemical Entities of Biological Interest (ChEBI)
A freely available dictionary of molecular entities focused on ‘small’ chemical compounds.
DrugBank
A unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The database contains 6707 drug entries including 1436 FDA-approved small molecule drugs, 134 FDA-approved biotech (protein/peptide) drugs, 83 nutraceuticals and 5086 experimental drugs.
AntibioticDB
The first free, open-access database of antibacterial compounds, including discontinued agents, drugs under pre-clinical development and those in clinical trials. This database includes over 1000 compounds.
Chemotext
Chemotext mines the published literature in PubMed using MeSH subject terms to enable text-based drug-target-disease relationships in order to identify novel drug repurposing candidates and discovery targets.
LIPID MAPS--Nature Lipidomics Gateway
The LIPID MAPS consortium provides a range of tools and resources to facilitate lipid research.
LipidBank
The official database of Japanese Conference on the Biochemistry of Lipids (JCBL)

Metabolics & Metabolome resources

Golm Metabolome Database
Facilitates the search for and dissemination of mass spectra from biologically active metabolites quantified using Gas chromatography (GC) coupled to mass spectrometry (MS).
METLIN -Metabolite and Tandem MS
METLIN is a metabolite database for metabolomics containing over 42,000 structures, it also represents a data management system designed to assist in a broad array of metabolite research and metabolite identification by providing public access to its repository of current and comprehensive MS/MS metabolite data.
MetaCyc Encyclopedia of Metabolic Pathways
MetaCyc is a database of nonredundant, experimentally elucidated metabolic pathways. MetaCyc contains more than 1790 pathways from more than 2216 different organisms, and is curated from the scientific experimental literature.
Human Metabolome Database (HMDB)
A freely available electronic database containing detailed information about small molecule metabolites found in the human body.

Proteins & Binding resources

BLAST - Basic Local Alignment Search Tool
BLAST finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.
RCSB Protein Data Bank
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function, and visualize, download, and analyze the results.
PROWL
Tools for searching and analyzing protein sequences based on mass spectroscopy.
Binding Database
BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of protein considered to be drug-targets with small, drug-like molecules.
CheShift - Validate your protein model
Enter a PDB (Protein Data Bank) format file of the protein model, and get back a list of predicted 13C chemical shifts for each amino acid residue in the sequence.
Kinase Knowledgebase
Eidogen-Sertanty's database of kinase structure-activity and chemical synthesis data.
DOCK Blaster
Public access service for structure-based ligand discovery. Aims to answer the question: What small molecules should I purchase and test for activity against my biological target for which I have a structure?
STITCH: chemical association networks
STITCH is a resource to explore known and predicted interactions of chemicals and proteins.

Locating Books: Library Catalogs

Library Catalogs usually list all of the materials available from a library, including books, theses and dissertations, government documents, audiovisual materials, electronic resources and databases, and journal and magazine subscriptions, but not individual journal articles.

You can always start with your local library catalog to see what items are in your campus library or can be sent from other campus libraries.

UToledo Library Catalog – (http://utmost.cl.utoledo.edu/)

The catalog can be searched by keyword or subject heading if have a topic and want to see what we have.
If you are looking for a specific item, you can search by Title or Author as well.
Click on any title to see more information. Use the Location & Call Number to locate an item in the library. Items that can be checked out will be marked as AVAILBLE. Items at other campus library locations can be sent to your nearest library using the Request button.

If you do not find the book you want in our local library catalog, or if our copy is checked out or missing, you can search our state-wide catalog.

OhioLINK Library Catalog – (http://olc1.ohiolink.edu/search/) Just like the UToledo Catalog, but lists materials in over 85 Ohio academic libraries. You can request books online to be sent to a UToledo library, in a matter of 3 – 5 days. To see if it has arrived, view your library record, or we’ll e-mail you to your @utoledo.edu account.

In the rare instance that you cannot find a book in the OhioLINK Library Catalog, you can search WorldCat to see if it exists in another library. Use the ILLiad Interlibrary Loan form to request that it be sent here.

UToledo Library Catalog Search

Or search the catalog and more with...

OhioLINK Catalog Search

EBook Collections

OhioLINK Electronic Book Center This link opens in a new window
- This link opens in a new window
Contains full text of thousands of scholarly books, reference books, and American and English literary works purchased by OhioLINK from numerous publishers.

Google Books
Books scanned and indexed from library copies and directly from publishers. Most are not available to see the full contents, but look for a 'Find in a Library' link on the left when viewing a book to see if we have it in print.