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Reviews and Evidence Syntheses: Integrative Review

Definition

Building upon the work of Broome (1993), Whittemore & Knafl (2005) define an integrative review as: " . . . a specific review method that summarizes past empirical or theoretical literature to provide a more comprehensive understanding of a particular phenomenon or healthcare problem (p. 546). 

Goal or Purpose Or Key Features

Integrative reviews are a common review type found in nursing, however a variety of other health sciences fields also utilize the integrative review methodology to synthesize literature. Conducting an integrative review is appropriate if you have a broad purpose statement/review question, and your aim is to comprehensively search the literature and review heterogenous research studies of varying types. 

Objectives

  • To broadly review studies of diverse and disparate types (i.e. experimental, non-experimental, quantitative, qualitative, etc.)
  • To present various perspectives on a clinical issue or phenomenon of concern
  • To integrate findings from the empirical and theoretical literature as a means to inform evidence-based healthcare decision-making and/or develop key concepts (Whittemore & Knafl, 2005)

Key Features

  • Broad purpose statement/research question
  • Comprehensive, reproducible search strategy
  • Use of search process flow diagram (i.e. PRISMA)
  • Literature representing diverse and disparate research methodologies (experimental, non-experimental, quantitative, qualitative, empirical, theoretical)
  • Eligibility screening (inclusion and exclusion criteria)
  • Critical appraisal of research literature
  • Narrative/thematic/descriptive/qualitative (non-statistical) synthesis of findings (Toronto & Remington, 2020)

Also see differences between integrative reviews and systematic reviews

Guidance

A seminal and classic article on integrative review methodology, and essential reading for anyone conducting an integrative review, is: 

Whittemore, R., & Knafl, K. (2005). The integrative review: Updated methodology. Journal of Advanced Nursing52(5), 546–553. https://doi.org/10.1111/j.1365-2648.2005.03621.x [click to read full-text]

The stages of an integrative review as outlined by Whittemore & Knafl (2005) are: 

  1. Problem identification
  2. Literature search 
  3. Data evaluation
  4. Data analysis
  5. Presentation

For updated guidance on conducting an integrative review, see:

Oermann, M. H., & Knafl, K. A. (2021). Strategies for completing a successful integrative review. Nurse Author & Editor (Wiley-Blackwell)31(3/4), 65–68. https://doi.org/10.1111/nae2.30 [click to read full-text]


The following book [available in E-Book or Print formats from the University Libraries] also provides thorough guidance on how to conduct an integrative review:

Integrative Review Vs. Systematic Review

What are the key differences between an integrative review and a systematic review?

  Integrative Review Systematic Review
Review protocol No Yes
Review question Broad purpose statement/review question(s) Single, focused clinical question often using the PICO format
Timeline (estimated) 6-12 months 12-24 months or more
Comprehensive, systematic, reproducible literature search strategies Yes Yes
Flow diagram of search process Yes (PRISMA flow diagram is recommended)  Yes (PRISMA flow diagram is the standard)
Inclusion and exclusion criteria Yes Yes
Sampling 

Heterogenous: 

Diverse array of research including experimental and non-experimental; quantitative and qualitative; empirical and theoretical literature

Homogenous:

1) Systematic review with meta-analysis: experimental, quantitative literature (i.e. randomized controlled trials only)

or

2) Systematic review with meta-synthesis: non-experimental, qualitative research literature

Critical appraisal Yes Yes
Data extraction Yes Yes
Data analysis/synthesis

Yes:

Narrative/thematic/descriptive/qualitative synthesis

Yes:

1) Systematic review with meta-analysis: quantitative synthesis using statistical techniques

or

2) Systematic review with meta-synthesis: qualitative synthesis

Toronto, C. E. (2020). Overview of the integrative review. In C. E Toronto & R. Remington (Eds.), A step-by-step guide to conducting an integrative review (p. 3). Springer. 

Exemplar Articles

The following articles are selected exemplary examples of integrative reviews. Prior to conducting your own integrative review, it will help to examine previously published examples from the literature. 

References

Librarian Support

How can University of Toledo librarians help with your integrative review?

  • Meet with you and/or members of your research team to talk about your topic and your search strategies, as well as databases and search terms that would be appropriate for your topic. [Schedule a Consult]
  • For faculty, resident physicians, fellows, and staff members: a librarian can do one search in a single database and email you the results. [Request a Search]

Note: Our services are only available to current UToledo faculty, resident physicians, fellows, students, and staff members. If you are affiliated with another institution, please contact your library to see what services are available for your review.