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Critical Appraisal Resources for Evidence-Based Nursing Practice

What is a Cohort Study?

A cohort study is a type of quantitative research.  They are often described as "natural experiments" (Schmidt & Brown, 2019, p. 210).  They are like case-control studies in reverse.  In a cohort study, individuals are selected based on their exposure status.  Researchers then investigate whether something individuals are exposed to is associated with the risk of a disease or condition (Schmidt & Brown, 2019, p. 210).  

Schmidt N. A. & Brown J. M. (2019). Evidence-based practice for nurses: Appraisal and application of research (4th ed.). Jones & Bartlett Learning. 

PRO TIPS: Cohort Study Checklist

Each JBI Checklist provides tips and guidance on what to look for to answer each question.  These tips begin on page 4. 

Below are some additional Frequently Asked Questions about the Cohort Studies Checklist that have been asked students in previous semesters. 

Frequently Asked Question Response
In regards to Question 4, what exactly is a confounding factor? A confounder or confounding factor/confounding variable is often referred to as a third variable that could potentially impact the study's results. Read a definition and description here. Confounding factors/variables or confounders may be listed in the study's limitations section or within the study's main results section. 
For Question 5, how can I tell whether strategies were used to deal with the confounding factors in the study? Check for multivariate analysis or regression analysis in the study's data analysis/statistical analysis section. Read a definition and description here

For more help: Each JBI Checklist provides detailed guidance on what to look for to answer each question on the checklist.  These explanatory notes begin on page four of each Checklist. Please review these carefully as you conduct critical appraisal using JBI tools. 

Articles on Cohort Study Design and Methodology

Cameron N. (2020). The growth and development of cohort studiesAnnals of Human Biology47(2), 89–93. https://doi.org/10.1080/03014460.2020.1727012

Euser, A. M., Zoccali, C., Jager, K. J., & Dekker, F. W. (2009). Cohort studies: Prospective versus retrospectiveNephron. Clinical Practice113(3), c214–c217. https://doi.org/10.1159/000235241

Nohr, E. A., & Liew, Z. (2018). How to investigate and adjust for selection bias in cohort studiesActa Obstetricia et Gynecologica Scandinavica97(4), 407–416. https://doi.org/10.1111/aogs.13319

Song, J. W., & Chung, K. C. (2010). Observational studies: Cohort and case-control studiesPlastic and Reconstructive Surgery126(6), 2234–2242. https://doi.org/10.1097/PRS.0b013e3181f44abc

Wang, X., & Kattan, M. W. (2020). Cohort studies: Design, analysis, and reportingChest158(1S), S72–S78. https://doi.org/10.1016/j.chest.2020.03.014