Animal Research Alternatives: Additional Resources/News

Over 100 Power Point slides. Outline related national law, regulations, polices, and guidelines. Overview of alternatives and the 3Rs. Includes database identification (as BIOSIS, Agricola), search tips, and search examples.

Information on methods and sources available to reduce, refine or replace animals used in teaching, testing, and research.

document was developed with input from members of 16 federal agencies, multiple interagency workgroups, and input from the public. As such, it represents a consensus perspective that does not necessarily reflect opinions or policy of any specific agency or workgroup, and should not be taken as a commitment by any federal agency.

Validates methods which reduce, refine or replace the use of animals for safety testing and efficacy/potency testing of chemicals, biologicals and vaccines.
Research laboratories are able to submit to EURL ECVAM for scientific validation the alternative methods to animal testing that they have developed.
EURL ECVAM also promotes the development and dissemination of alternative methods and approaches, their apEURL-ECVAMplication in industry and their acceptance by regulators.

FRAME’s ultimate aim is the elimination of the need to use laboratory animals in any kind of medical or scientific procedures.
FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused.

Includes programs, activities, publications, online newsletter, resources (including free online classes) and link to AltWeb - "the global resource for information on alternatives to animal testing"

supports the development, validation and implementation of innovative scientific methodologies that advance science and replace the use of animals in research, testing and education.

IFER bridges the gap between the ethical concerns of people who oppose the suffering of animals and the concerns of scientists who recognize the limitations of other species to model human diseases and to predict what is safe and effective for people.

IIVS couples scientific and compliance programs with education and outreach initiatives to promote the use and acceptance of these methods worldwide.

Resource for untrained database users. Thorough guide to comprehensive searches as required by law. Most content applicable to US researchers.
Includes the 3Rs.

Publicly available big data from regulatory submissions has been compiled in the PharmaPendium database to establish concordance, or consistency, between adverse events reported in animals and in humans. The result is a database that can help curb the amount of animal testing needed while still enabling companies to meet safety and regulatory requirements.